Welcome to Cain's Bar-B-Que, a true gem nestled in Florence, South Carolina. Located at 1502 Pamplico Hwy, this beloved establishment has earned its place in the hearts (and stomachs) of locals and visitors alike. Known for its outstanding southern cuisine, Cain's Bar-B-Que delivers a delightful experience of warmth and familiarity that makes every guest feel like part of the family.

At Cain's, the menu is a celebration of southern comfort food. The star attractions include mouthwatering barbecue pork and chicken, complemented by a variety of side items that are sure to satisfy any craving. Guests rave about the fried chicken which boasts a crispy, golden exterior and tender, juicy meat. Pair it with mac and cheese that rivals even grandma's Thanksgiving spread, and you'll see why diners leave raving.

As Liza Miller beautifully encapsulated, dining here feels like a homecoming. The atmosphere is filled with laughter and chatter, where no one is a stranger and every meal is shared with love. Not to mention, the abundance of sides like chicken bog, string beans, and yams complement the main dishes perfectly, making each visit a culinary adventure.

But don't just take our word for it. Patrons like Rhonda Hatfield and James Jordan sing praises for the delicious offerings, with mentions of the delectable chicken and rice, and, if you're lucky enough, the coveted potato casserole. With each bite, you can savor the rich, homestyle flavors that make southern cooking legendary.

Whether you're grabbing a bite for a casual lunch or planning a family gathering, Cain's Bar-B-Que promises a feast that leaves you wanting more. With friendly service, a welcoming vibe, and quality food that brings people together, it's no wonder why this place has become a top choice for many in the Florence area. Come join the celebration of good food and great company at Cain's Bar-B-Que—you won't regret it!